USB Keyboard and Mouse Stop Working Sometimes

USB Keyboard and Mouse Stop Working Sometimes

Recently my USB keyboard and mouse has been stopping working randomly
every once in a while, and only working again after I restart my laptop.
Putting them in different usb slots doesn't help, and other devices like
mp3 players still work in the same usb slot. Tried using another mouse,
still didn't work, but the original one worked on a different laptop. I
can't see a pattern in when they stop working, and there's no recurring
events.
I have windows 7, mouse is a wired optical Logitech, keyboard is a simple
wired microsoft one. I have updated and uninstalled and re-installed the
drivers, ran anti-virus and malware scans, and it hasn't helped. Any
ideas?
Thanks